HSCI 430 Assignment

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HSCI 430 Assignment. This week you read about organization dynamics that influence health disparities in diverse populations. Review the questions below and reflect on what you learned. Answer the questions by reflecting on what you learned and synthesizing that information to create solutions. 

1. Imagine you are the CEO of a health care clinic in a rural area. Over the past five years, there have been increasing complaints about the lack of diversity in age among the clinic staff. In particular, complaints have skyrocketed regarding the young staff and lack of cultural sensitivity to the aging population. The board of trustees is concerned and called a meeting with you to discuss this. During the meeting, they blamed you for not ensuring better age diversity in staff. Now you must respond and remedy the situation. You were told to create policies and practices to increase diversity.

a. Identify two policies (i.e. rules) and practices (i.e. procedures) the clinic will begin implementing that will help in the recruitment and retention of older staff.

b. Describe how and why these policies and practices would be beneficial to the clinic.

c. Then, describe how the same policies might benefit employees from other groups, for example, individuals of a different age, gender, race, ethnicity, religion, and so on. In other words, how might these policies and practices benefit those who are different from the older staff?

2. Refer to Figure 3.1 in your text. How do you think the social factors that contribute to disparities in workforce for minorities can be overcome? Hypothesize one micro, one mezzo (meso), and one macro level practice that can be done to change the workforce and career outcomes shown in the figure. You should come up with a total of three ideas.

If you need clarity about the difference between micro and macro, here is an article that provides an excellent breakdown using the field of social work: https://dworakpeck.usc.edu/news/do-you-know-the-difference-between-micro-mezzo-and-macro-level-social-work

Micro idea:

Mezzo idea:
Macro idea:

3. Review the healthcare organization checklist from chapter three in your text. If you work in a health care organization, use the assessment checklist in this chapter to evaluate the organization’s responsiveness to diversity. If you do not work in a health care organization, use the checklist to evaluate a health clinic that you are a patient at. Another option is to evaluate your place of employment or your academic institution. Though all items on the list may not fully apply, it is still ok to use these organizations to complete the assignment. Later in the course you will complete an organizational assessment (ORGANX) so it is important for you to become familiar with evaluating organizations now.

a. What are the organization’s areas of strength?

b. Which areas need the most improvement?

HSCI 430 Assignment

 
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BIO – Evaluate The Following Lac Operon Partial Diploids

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BIO – Evaluate The Following Lac Operon Partial Diploids. 1. (1 point) Evaluate the following lac operon partial diploids. Indicate whether the production of functional β-galactosidase from lacZ and of permease from lacY is “inducible”, “constitutive”, “absent” or “noninducible” for each partial diplod
a. F’ I+-p+o+Z+Y+ X F- I+p+o+Z-Y-
b. F’ I+-p+ocZ+Y- X F- I+p+o+Z-Y+ c. F’ I+-p+ocZ-Y+ X F- Isp+o+Z+Y+
2~3 Describe the effects on attenuation and on tryptophan synthesis of the following mutations of the two tryptophan codons (UGGUGG) in the attenuator region of operon.
2. (1 point) The tryptophan codons are mutated to UAGUGG. 3. (1 point) The tryptophan codons are mutated to UUGUUG.
4. (1 point) What would be the phenotype of a null mutation in the CRP protein gene in the regulation of Lac operon and why?
5. (1point) What would be the phenotype of a “constitutively expressed” mutation in the CRP protein gene in the regulation of Lac operon (i.e. CRP proteins are always highly expressed) and why?
6. (2 points) A repressible operon system, like the trp operon, contains three genes, G, Z, and W. Operon genes are synthesized when the end product of the operon synthesis pathway is absent, but there is no synthesis when the end product is present. One of these genes is an operator, one is a regulatory protein, and the other is a structural enzyme involved in synthesis of the end product. In the table below, “+” indicates that the enzyme is synthesized by the operon, and “-“ means that no enzyme synthesis occurs. Use this information to determine which gene corresponds to each operon function.
Present
G+Z+W+   +
G-Z+W+   + G+Z-W+   – G+Z+W-      + G-Z+W+/G+Z-W-      + G+Z-W+/G-Z+W-      + G-Z-W-/G+Z+W+      + G+Z+W-/G-Z-W+      +
7. (1 point) Gene A is maternally imprinted (silenced) while Gene B is paternally imprinted when imprinted silencing occurs. A Mom with Genes A and B imprinted and a Dad with an imprinted Gene A have a daughter and a son. The children then marry individuals known not to be silenced for either gene. What is the imprint status of the daughter and son respectively? If each marriage results in the birth of a daughter and a son, what would you expect the imprint status of genes A and B to be for the grandchildren?
8 ~ 9. On a rare occasion, human can be born with a condition known as “uniparental disomy”. This happens when an individual inherited both copies of a chromosome from one parent but no copies from the other parent. For example, abnormal sperm that lacks chromosome 15 can fertilize an egg that contains two copies of chromosome 15. This is known as maternal uniparental disomy 15. Alternatively, there are cases of paternal disomy 15 (an abnormal sperm with two copies of chromosome 15 fertilizes an egg with no copies).
8. (1 point) If a female is born with paternal disomy 15, would you expect her to be normal or have Angelman syndrome (AS) or have Prader-Willi syndrome (PWS)? And explain why?
9. (1point) Would you expect her to produce normal offspring or offspring affected with AS or PWS?

BIO – Evaluate The Following Lac Operon Partial Diploids

 
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“Tarnita’s Termites, Pacific Lampreys, And Large Brains”

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“Tarnita’s Termites, Pacific Lampreys, And Large Brains”. “Tarnita’s Termites, Pacific Lampreys, and Large Brains”

For your primary post, please respond to one of the following three topics with a post of at least 125 words that addresses each point given in the instructions. Also, please reply to at least one fellow student on any topic.

Topic 1

: Population Distribution of Termites in a Savanna. Watch the video (1) describing Corina Tarnita’s research on the spacing of termite mounds in savanna ecosystems, and then address the following:

  • (a) What were Tarnita’s findings about the spacing of termite mounds?
  • (b) What does Tarnita think is the main factor that governs the spatial distribution of the termite mounds?
  • (c) How do the termite mounds benefit other organisms on the savanna?

Topic 2

:  Pacific Lampreys. Watch the video about Pacific Lampreys (2)*, then address the following:

  • (a) Where do Pacific lampreys fall in the taxonomy of vertebrates?
  • (b) What challenges do Pacific lamprey populations face?
  • (c) Why are Native American tribes of the Northwest concerned about them? (Please note: take care not to confuse the Pacific lamprey (described in the video) with the Sea Lamprey, which is a completely different species that is considered an invasive species in the Great Lakes).

Topic 3 [article]: Supporting the Energy Needs of a Large Brain. As discussed in the article by Zimmer (3)*, brain tissue is energetically expensive. For a species to evolve a large brain, it may need to make certain adjustments to ensure that enough energy is available to support brain function. Zimmer discusses various hypotheses about such adjustments in the human line of descent. Explain one of these adjustments.

References (in Strayer Writing Standards format).

  1. HHMI Biointeractive (2015, November 11). Analyzing patterns in the savanna landscape. [Video]. Retrieved from https://youtu.be/nJGpABrEatc
  2. U.S. Fish & Wildlife Service. (2012). Taking the initiative to conserve Pacific Lamprey. [Video]. Retrieved from https://www.youtube.com/watch?v=dkwfDVAoSXk
  3. Carl Zimmer, July/August 2011. The brain. Discover, 32 (6), 18-19. https://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=61992134&site=ehost-live&scope=site

“Tarnita’s Termites, Pacific Lampreys, And Large Brains”

 
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Biological Basis Assignment 2:

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Biological Basis Assignment 2:. Assignment 2: Biological Basis

Due in week 5 and worth 80 points

Continuing on the research that you started in Week 3, explain what your chosen biotechnology accomplishes and how it is implemented, and describe the body of knowledge that it is based upon. The detailed guidelines are as follows:

  • Begin with a description of the biotechnology and what it accomplishes. Then, explain whether it involves manipulating the DNA (or RNA) of an organism, or simply utilizing the DNA (or RNA) that is already there naturally.
  • Provide a full and complete description of exactly how the technology works.
    • If your technology involves manipulating the DNA of an organism, then you should explain how that is accomplished. Depending on the specific technology, adding DNA to cells is often accomplished with a vector, such as a virus or bacterium, but there are mechanical means as well, such as microinjection or use of a “gene gun.”
    • If your technology involves interpreting the DNA in an organism (as one might do for personalized medicine), explain how that is accomplished. What are the means of collecting a sample? How is the sample processed? What exactly is being analyzed to generate the interpretation?
  • Discuss the key biological principles that underlie the technology. Many of them are based on an understanding of genes and how they are expressed. Other technologies may be based on the concept of the genome, transcriptome, or proteome. Others are based on an understanding of non-coding DNA (such as the short-tandem repeats used in DNA fingerprinting). Many are based on an understanding of DNA replication, as well as basic heredity.

The expected length is a proxy for how much detail to go into. Go into enough detail to get at least one page of double-spaced text (about 300 words), but not much more than two pages of double-spaced text (about 600 words).  Your overall goal in this assignment is to show the instructor that you understand the underlying science behind the technology.

You must have a reference section which contains an SWS reference to your chosen article and all other sources. Additionally, you must provide in-text citations (in SWS format) to your references in the body of the text. Integrate all sources into your paper using proper techniques of quoting, paraphrasing and summarizing, along with your in-text citations. Double-space your paper. Use standard margins and fonts. Also, follow any additional formatting instructions provided by your instructor.

A large portion of the grading of this assignment is based upon the coherence, depth, and accuracy of your writing.

Objectives evaluated by this assessment:

  1. Categorize a wide range of organisms, from single-celled to multi-celled organisms.
  2. Describe how organisms acquire and utilize both energy and material.
  3. Describe the cell cycle, cell reproduction, and control.
  4. Investigate DNA and gene expression as well as technologies based on our understanding of them.
  5. Discuss interactions between organisms in ecosystems.

Biological Basis Assignment 2:

 
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